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Zantac Users Should Consider Safer Alternative Drugs

The FDA has issued a list of drugs they have preliminarily tested and found to be safe from elevated levels of NDMA

Wednesday, July 1, 2020 - Heartburn and acid-reflux sufferers that have been left in the lurch by the recall of Zantac, the world's best-selling heartburn medicine, have several alternatives to choose from to alleviate the painful burning in their stomach and chest. Over the counter and prescription medication, Zantac was voluntarily withdrawn from the market because it contains unsafe levels of NDMA, a by-product of manufacturing rocket fuel, and a carcinogen given to lab test animals to induce tumors to be studied. Zantac was removed from the shelves of pharmacies like Walmart, Walgreens, Rite Aid, and CVS. The US Food and Drug Administration (FDA) has produced a list of Zantac-replacement drugs that were recently tested and found to be safe. The FDA recommends Zantac users to consider taking Pepcid (famotidine), Tagamet (cimetidine), Nexium (esomeprazole), Prevacid (lansoprazole) or Prilosec (omeprazole), all of which have had favorable test results.

According to Wikipedia, "Pepcid, (Famotidine), is a medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour. Tagamet, (cimetidine), is a histamine H₂ receptor antagonist that inhibits stomach acid production. Nexium (esomeprazole), reduces stomach acid. It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger-Ellison syndrome. Effectiveness is similar to other proton pump inhibitors. It is taken by mouth or injection into a vein." Proton Pump Inhibitor (PPI) drugs work by shutting the release of digestive acids in the stomach. They are not intended for immediate relief and can take up to 4 days to become fully effective. PPI drugs are required to be taken daily to be effective and therein may lie the problem. Zantac users have filed suit against Sanofi, the maker of Zantac, alleging that taking the drug regularly for an extended time exposed them to carcinogenic levels of NDMA. Zantac users have allegedly developed cancer of the stomach, bladder, esophagus, prostate, pancreas, breast, and other forms of cancer. Many have hired Zantac Cancer Attorneys to file a claim against Sanofi for failing to warn them of the dangers of taking the drug.

Zantac has been available to the public since the 1980s and sales have exceeded $10 billion per year for over a decade. The recall deals a severe blow to Sanofi, the maker of Zantac, and also generic ranitidine manufacturers Generic drugmakers Perrigo, Novartis, and Apotex which all followed suit and immediately recalled their heartburn drugs. NDMA is an environmental contaminant found in water and most foods at levels assumed to be safe for human consumption. Researchers think that heating ranitidine to levels that mimic those found in the human stomach can cause ranitidine to break down and NDMA to increase to levels in the millions of nanograms per dosage. The allowable FDA level of NDMA is only 96 nanograms.

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OnderLaw, LLC is a St. Louis personal injury law firm handling serious injury and death claims across the country. Its mission is the pursuit of justice, no matter how complex the case or strenuous the effort. The Onder Law Firm has represented clients throughout the United States in pharmaceutical and medical device litigation such as Pradaxa, Lexapro and Yasmin/Yaz, where the firm's attorneys held significant leadership roles in the litigation, as well as Actos, DePuy, Risperdal and others. The Onder Law Firm has won more than $300 million in four talcum powder ovarian cancer lawsuits in St. Louis. Law firms throughout the nation often seek its experience and expertise on complex litigation.


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