Ranitidine Is Unstable According to Valisure

A Valisure study indicates that ranitidine, and not outside contamination, is the cause of NDMA's formation

Tuesday, February 2, 2021 - Scientists at the Food and Drug Administration and private companies have struggled with pinpointing the cause of Zantac's cancer contamination. In 2019, online drug testing pharmacy Valisure alerted the FDA that Zantac and all other ranitidine drugs tested positive for dangerously elevated levels of NDMA, a known carcinogen. Many suspects have emerged over the year since Sanofi, the maker of Zantac, voluntarily recalled the drug a couple of months before the FDA banned all ranitidine. NDMA levels far exceeded the 96NGs that the FDA thought were safe. The FDA's concern about Zantac's safety was multiplied by the fact that Zantac was the world's best-selling heartburn and antacid drug, with over 15 million customers per year. Over 100 million people around the world reach for or take heartburn medicine preemptively every year. If Zantac did cause cancer, millions of people could have been affected. Individuals that have used Zantac regularly and have developed stomach, bladder, of other types of cancer, are encouraged to speak with a Zantac Cancer Lawyer.

The ranitidine (Zantac) cancer scare may be unique to ranitidine and different from other drugs that have tested positive for elevated levels of N-Nitrosodimethylamine (NDMA). According to statements made recently by David Light, CEO of online drug testing pharmacy Valisure, ranitidine degrades on its own when stored at higher than regular temperatures and also degrades when interacting with nitrates in the stomach, making it an inherently unstable molecule. CEO Light and other opinions regarding ranitidine's inherent instability were published on January 29, 2021, in the Journal of American Medicine Association (JAMA). Other drugs like blood pressure pills and type 2 diabetes medicine metformin, are said to have been NDMA contaminated at the manufacturing source in China. Valisure's logic in making the determination was reiterated by Kaury Kucera, Ph.D., chief scientific officer at the company as follows: "Valisure detected NDMA in every brand and every dosage form of ranitidine that we tested whether over the counter or prescription and regardless of manufacturer. This appears to be a fundamentally different problem than NDMA contamination found in drugs like valsartan and metformin because it occurs in every brand of ranitidine and is inherent to the molecule itself."

Pinpointing the cause of NDMA formation is important to those who have developed cancer and now seek to hold Sanofi accountable. Sanofi is being accused by the US Department of Justice of lying about their knowledge of ranitidine degrading into NDMA. For more than two decades, Zantac was the world's leading seller of heartburn and acid reflux medicine and its maker had a vested interest in keeping quiet. A Reuters article about the investigation states, "The U.S. Department of Justice has opened an investigation into whether drugmakers including Sanofi SA failed to disclose to the federal government information about the potential presence of a probable carcinogen in the heartburn drug Zantac." Thousands of plaintiffs with Zantac-related cancer eagerly await the outcome of the investigation.

More Recent Heartburn MedicineLawsuit News:

• Zantac Cancer Trials Are In Discovery To Begin In October 2022 | 7/19/2022
• Zantac Cancer Lawsuits Could Hinge On The Validity of Ranitidine Testing Methods | 7/11/2022
• Zantac Cancer Bellwether Trials In California Could Set The Stage For A Global Settlement Offer | 7/5/2022
• The FDA Recommended Protein Pump Inhibitor Drugs Like Prilosec And Nexium That May Damage Health More Than Zantac | 6/23/2022
• Truck Drivers, Firefighters, and Police Officers May Have Taken More Zantac Than People In Other Occupations | 6/20/2022
• Scientists Are Expected To Confirm That Ranidine Causes Gastrointestinal Cancer With Slam Dunk Testimony | 6/9/2022
• Scientific Hearings Will Start This September To Interview Zantac Cancer Expert Witnesses | 5/19/2022
• A Whistleblower Scientist Working For A Chinese Company Thinks NDMA Contamination Started In China | 5/12/2022
• Valisure's String Of Stunning Success Casts Doubt On The FDAs Ability To Police The Health Care Market | 5/2/2022
• Zantac Testing Accusations Heat Up With FDA Investigation Of Online Prescription Drug Testing Lab | 4/25/2022
• Study Finds Ranitidine Degrades Into 10,000 Nanograms of NDMA When Introduced To Simulated Stomach Conditions | 4/6/2022
• Potential Zantac Expert Witnesses Are Being Questioned By Zantac Defense Attorneys | 3/31/2022
• The FDA Requires That Drug Companies Regularly Test Ranitidine And Other Drug For NDMA | 3/24/2022
• Update: Where The Zantac Cancer Multidistrict Litigation (MDL) Stands Today | 3/12/2022
• Zantac Cancer Plaintiffs Look To The First Trial In October In Alameda California | 3/11/2022
• Zantac Cancer Plaintiffs Have Until June 30 To Finalize Their Claim | 3/7/2022
• Zantac Bellwether Trials May Focus On Ranitidine Testing Methods That Could Cause NDMA To Accelerate | 3/1/2022
• Valisure LLC's Motivations And Ranitidine Testing Methods May Not Be Scrutinized Before Trial | 2/24/2022
• Zantac Lawsuits May Go To Trial In California In October Of This Year | 2/18/2022
• Sanofi's History Of Reprehensible Corporate Behavior May Bolster Zantac Cancer Lawsuits | 2/10/2022

Lawyers for Zantac Heartburn Medicine Lawsuits

OnderLaw, LLC is a St. Louis personal injury law firm handling serious injury and death claims across the country. Its mission is the pursuit of justice, no matter how complex the case or strenuous the effort. The Onder Law Firm has represented clients throughout the United States in pharmaceutical and medical device litigation such as Pradaxa, Lexapro and Yasmin/Yaz, where the firm's attorneys held significant leadership roles in the litigation, as well as Actos, DePuy, Risperdal and others. The Onder Law Firm has won more than $300 million in four talcum powder ovarian cancer lawsuits in St. Louis. Law firms throughout the nation often seek its experience and expertise on complex litigation.